Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IARS1 | P41252 | 6/20 | 0.34 |
| ▸ | DPP4 | P27487 | 11/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129694 | 0.89 | MGAM (0.34) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL8129238 | 0.86 | PSMB5 (0.34) | — | |
| SCHEMBL8125647 | 0.84 | IARS1 (0.32) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL8119566 | 0.84 | DPP4 (0.39) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL8120903 | 0.81 | DPP4 (0.37) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL8121069 | 0.80 | DPP4 (0.36) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8131712 | 0.79 | SLC15A1 (0.52) | — | |
| SCHEMBL8120553 | 0.78 | MGAM (0.35) | — | |
| SCHEMBL8148377 | 0.78 | DPP4 (0.36) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL8129583 | 0.77 | DPP4 (0.39) | IARS1DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |