Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349353 | 0.82 | KDM4E (0.38) | KDM4EMAPTGABRPGABRDGABRA1 | |
| SCHEMBL7714810 | 0.77 | TSHR (0.39) | KDM4EMAPTGABRPGABRDGABRA1 | |
| SCHEMBL6614933 | 0.77 | MAPT (0.40) | KDM4EMAPTMEN1HPGDKMT2A | |
| SCHEMBL19747000 | 0.70 | MAPT (0.43) | KDM4EMAPTGABRPGABRDGABRA1 | |
| SCHEMBL6351873 | 0.69 | PRKAB2 (0.43) | KDM4EMAPTALDH1A1 | |
| SCHEMBL6341328 | 0.67 | NR4A2 (0.38) | — | |
| SCHEMBL29530477 | 0.65 | KDM4E (0.81) | KDM4EMAPTCDK2BLMDRD2 | |
| SCHEMBL2638095 | 0.65 | KDM4E (0.81) | KDM4EMAPTCDK2BLMDRD2 | |
| SCHEMBL5205301 | 0.64 | GABRA1 (0.39) | KDM4EMAPTGABRA1TSHRGABRB1 | |
| Hydrochloric Acid SCHEMBL698487 | 0.64 | KDM4E (0.78) | KDM4EMAPTCDK2BLMDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040103-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |