Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5079505 | 0.97 | MAPT (0.39) | MAPTCHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL5080404 | 0.92 | MAPT (0.35) | MAPT | |
| Hydrochloric Acid SCHEMBL5077611 | 0.90 | MAPT (0.34) | MAPTACHE | |
| Hydrochloric Acid SCHEMBL5084131 | 0.88 | NPC1 (0.34) | MAPT | |
| Hydrochloric Acid SCHEMBL5080418 | 0.88 | KEAP1 (0.33) | MAPT | |
| Hydrochloric Acid SCHEMBL5079586 | 0.86 | MAPT (0.32) | MAPT | |
| Hydrochloric Acid SCHEMBL5083419 | 0.85 | MAPT (0.30) | MAPT | |
| Hydrochloric Acid SCHEMBL1481260 | 0.85 | HTR2C (0.34) | MAPT | |
| Hydrochloric Acid SCHEMBL5077685 | 0.84 | ALDH1A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL399507 | 0.84 | MRGPRX4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464670-B1 | PROCESSES FOR CONTROLLING THE VISCOSITY OF POLYALPHAOLEFINS | CHEMTURA CORP (US) | 2014-11-19 | — | — | EP | claimed |
| EP-2464670-A1 | PROCESSES FOR CONTROLLING THE VISCOSITY OF POLYALPHAOLEFINS | Chemtura Corporation (US) | 2012-06-20 | — | — | EP | claimed |
| US-8067652-B2 | Processes for controlling the viscosity of polyalphaolefins | CHEMTURA CORPORATION (US) | 2011-11-29 | — | — | US | claimed |
| WO-2011019541-A1 | PROCESSES FOR CONTROLLING THE VISCOSITY OF POLYALPHAOLEFINS | CHEMTURA CORPORATION (US) | 2011-02-17 | — | — | WO | claimed |
| US-20110040052-A1 | Processes for Controlling the Viscosity of Polyalphaolefins | LANXESS SOLUTIONS US INC. | 2011-02-17 | — | — | US | claimed |
| EP-2464670-B1 | PROCESSES FOR CONTROLLING THE VISCOSITY OF POLYALPHAOLEFINS | CHEMTURA CORP (US) | 2014-11-19 | — | — | EP | disclosed |
| EP-2395028-A1 | Process for removal of residual catalyst components | Chemtura Corporation (US) | 2011-12-14 | — | — | EP | disclosed |
| US-8067652-B2 | Processes for controlling the viscosity of polyalphaolefins | CHEMTURA CORPORATION (US) | 2011-11-29 | — | — | US | disclosed |
| EP-2059538-B1 | PROCESS FOR REMOVAL OF RESIDUAL CATALYST COMPONENTS | CHEMTURA CORP (US) | 2011-10-19 | — | — | EP | disclosed |
| US-7943807-B2 | Controlling branch level and viscosity of polyalphaolefins with propene addition | CHEMTURA CORPORATION (US) | 2011-05-17 | — | — | US | disclosed |
| US-20110092752-A1 | Polyalphaolefins and processes for forming polyalphaolefins | CHEMTURA CORPORATION, a corporation of the State of Delaware | 2011-04-21 | — | — | US | disclosed |
| US-20110040052-A1 | Processes for Controlling the Viscosity of Polyalphaolefins | LANXESS SOLUTIONS US INC. | 2011-02-17 | — | — | US | disclosed |
| WO-2003051943-A1 | PROCESS FOR THE OLIGOMERIZATION OF αOLEFINS HAVING LOW UNSATURATION, THE RESULTING POLYMERS, AND LUBRICANTS CONTAINING SAME | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2003-06-26 | — | — | WO | disclosed |
| EP-1309633-A2 | PROCESS FOR PRODUCING LIQUID POLYALPHAOLEFIN POLYMER, METALLOCENE CATALYST THEREFOR AND LUBRICANTS CONTAINING THE SAME | Uniroyal Chemical Company, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0892816-B1 | POLYMERIZATION PROCESS FOR PRODUCING POLYOLEFIN ELASTOMER, CATION-GENERATING COCATALYST FOR ACTIVATING A METALLOCENE PROCATALYST, POLYOLEFIN ELASTOMER POSSESSING A UNIQUE COMBINATION OF PROPERTIES AND PRODUCTS MANUFACTURED THEREFROM | UNIROYAL CHEM CO INC (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2002014384-A2 | PROCESS FOR PRODUCING LIQUID POLYALPHAOLEFIN POLYMER, METALLOCENE CATALYST THEREFOR AND LUBRICANTS CONTAINING THE SAME | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
| US-6225426-B1 | LIQUID PHASE POLYMERIZATION OF ETHYLENE, ALPHA-OLEFIN AND DIENE IN PRESENCE OF CATALYST COMPRISING MIXTURE OF METALLOCENE PROCATALYST AND ALUMINOXANE OR ALUMINOXANE AND TRIALKYLALUMINUM COMPOUND TOPRODUCE ELASTOMER | UNIROYAL CHEMICAL COMPANY, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6147025-A | SUBSTITUTING PART OR ALL OF THE ALUMINOXANE COCATALYST WITH A CATION-GENERATING COCATALYST | UNIROYAL CHEMICAL COMPANY, INC, (US) | 2000-11-14 | — | — | US | disclosed |
| US-6136744-A | CATION-GENERATING COCATALYST COMPRISES A METAL COMPONENT, E.G., AN ALUMINUM COMPOUND, (2) A NEUTRAL METAL CONTAINING COMPONENT, E.G., A BORANE COMPOUND, AND (3) AN ANIONIC METAL COMPONENT, E.G., A METAL TETRAKIS(TETRAFLUOROPHENYL)BORATE. | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-10-24 | — | — | US | disclosed |
| US-6060572-A | LIQUID PHASE POLYMERIZATION OF ETHYLENE AND AT LEAST ONE OTHER ALPHA-OLEFIN USING A BULKY METALLOCENE CATALYST ACTIVATED BY AN ALUMOXANE OR A CATION-GENERATING METALLOCENE; HIGH MOLECULAR WEIGHT; HIGH VISCOSITY; LOW POLYDISPERSITY | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092752-A1 | Polyalphaolefins and processes for forming polyalphaolefins | PAOX, ALOX12, ALOX15 | CHRM2 2203/4885CHRM1 1477/4885ACHE 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.