Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804607 | 0.79 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL10338935 | 0.79 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL16958914 | 0.79 | LMNA (0.55) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL29724084 | 0.79 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL32671492 | 0.79 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL11443433 | 0.78 | LMNA (0.48) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL4331368 | 0.73 | ALOX5 (0.47) | LMNACYP1A2CYP2A6KDM4EMAPT | |
| SCHEMBL23707000 | 0.72 | TRPA1 (0.62) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL29484749 | 0.72 | TRPA1 (0.62) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL11373224 | 0.71 | GABRA1 (0.44) | LMNASLC6A2HTR2BCYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968159-A1 | METHOD FOR PREPARATION OF STYRENES | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998032719-A1 | METHOD FOR PREPARATION OF STYRENES | AVENTIS RESEARCH & TECHNOLOGY GMBH & CO KG (DE) | 1998-07-30 | — | — | WO | disclosed |