SCHEMBL813446

SCHEMBL813446

NN(C(=O)CCC(=O)N(N)C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
MAPT P10636 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
HPGD P15428 3/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
POLB P06746 1/20 0.43
PARP1 P09874 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
HSD17B10 Q99714 1/20 0.43
LMNA P02545 1/20 0.42
NR4A2 P43354 1/20 0.42
CES1 P23141 3/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6323030 0.94 NR4A2 (0.52) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL815273 0.92 L3MBTL1 (0.48) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL813218 0.90 L3MBTL1 (0.52) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL815038 0.90 L3MBTL1 (0.52) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL814104 0.90 L3MBTL1 (0.52) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL500478 0.90 L3MBTL1 (0.52) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL27775978 0.89 ADRA2C (0.39) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL10593483 0.89 CES2 (0.50) L3MBTL1MAPTHPGDALDH1A1LMNA
SCHEMBL6323023 0.88 L3MBTL1 (0.51) ADRA2CL3MBTL1MAPTTDP1HPGD
SCHEMBL64274 0.84 TDP1 (0.52) ADRA2CL3MBTL1MAPTTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140296399-A1 PROCESS FOR PRODUCTION OF POLYLACTIC ACID RESIN COMPOSITION KAO CORP (JP) 2014-10-02 US disclosed
US-8785520-B2 Process for production of polylactic acid resin composition KAO CORPORATION (JP) 2014-07-22 US disclosed
EP-2199052-B1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORP (JP) 2014-01-22 EP disclosed
US-20120296017-A1 PROCESS FOR PRODUCTION OF POLYLACTIC ACID RESIN COMPOSITION KAO CORPORATION (JP) 2012-11-22 US disclosed
US-8062574-B2 Process for production of injection-molded article of polylactic acid resin KAO CORPORATION (JP) 2011-11-22 US disclosed
US-20100201037-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORPORATION (JP) 2010-08-12 US disclosed
EP-2199052-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN Kao Corporation (JP) 2010-06-23 EP disclosed