Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122612 | 0.86 | MEN1 (0.33) | MAPTLMNAXDHKDM4EALDH1A1 | |
| SCHEMBL8128422 | 0.85 | FABP4 (0.34) | MAPTLMNAXDHPOLB | |
| SCHEMBL8549368 | 0.83 | ALDH1A1 (0.38) | MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL8135092 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7997430 | 0.72 | LTB4R (0.39) | MAPTLMNAXDHKDM4EALDH1A1 | |
| SCHEMBL26606801 | 0.72 | LMNA (0.46) | PARP1MAPTLMNA | |
| SCHEMBL8135015 | 0.70 | NPSR1 (0.37) | MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL6732023 | 0.69 | BAZ2B (0.38) | MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL15344152 | 0.69 | LMNA (0.38) | PARP1MAPTLMNA | |
| SCHEMBL8871670 | 0.68 | GAA (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |