Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | F13A1 | P00488 | 2/20 | 0.31 |
| ▸ | TGM2 | P21980 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962253 | 0.82 | MMP1 (0.46) | BCL2L1MCL1FFAR1FFAR4MMP1 | |
| SCHEMBL12386985 | 0.57 | LTA4H (0.50) | BCL2L1MCL1SCN9AFFAR1FFAR4 | |
| SCHEMBL15742443 | 0.56 | MAPT (0.38) | — | |
| SCHEMBL15910197 | 0.56 | HSPB1 (0.48) | KCNH2SCN9AFFAR1FFAR4EPHX2 | |
| SCHEMBL6070160 | 0.56 | GRM2 (0.38) | — | |
| SCHEMBL255272 | 0.56 | LTA4H (0.67) | SCN9AFFAR1FFAR4EPHX2LTA4H | |
| SCHEMBL19852061 | 0.55 | ALDH1A1 (0.40) | — | |
| Methylamine SCHEMBL28014353 | 0.55 | LTA4H (0.57) | SCN9AFFAR1FFAR4EPHX2LTA4H | |
| SCHEMBL9814841 | 0.54 | SRD5A2 (0.72) | BCL2L1MCL1LTA4H | |
| SCHEMBL19629839 | 0.54 | KMT2A (0.41) | MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977733-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | Pfizer Products Inc. (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998033768-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1998-08-06 | — | — | WO | disclosed |