Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926736 | 0.83 | METAP2 (0.45) | ALDH1A1LMNAMAPTMETAP2METAP1 | |
| SCHEMBL2879497 | 0.82 | METAP2 (0.60) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL6551588 | 0.81 | TDP1 (0.53) | ALDH1A1MAPTKDM4EHPGDMETAP2 | |
| SCHEMBL64533 | 0.81 | KMT2A (0.62) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL2881876 | 0.79 | TUBB4A (0.63) | ALDH1A1LMNAMEN1ESR1GAA | |
| SCHEMBL8434497 | 0.77 | HSD11B1 (0.48) | ALDH1A1METAP2METAP1MEN1ESR1 | |
| SCHEMBL929164 | 0.77 | ALPL (0.53) | ALDH1A1LMNAMAPTMETAP2METAP1 | |
| SCHEMBL2884331 | 0.76 | MEN1 (0.52) | ALDH1A1LMNAMAPTMETAP2METAP1 | |
| SCHEMBL4538720 | 0.76 | PLCG1 (0.45) | ALDH1A1LMNAMAPTKDM4ETHRB | |
| SCHEMBL28100041 | 0.74 | KMT2A (0.54) | ALDH1A1LMNAMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063545-A | Negative-working radiation-sensitive mixture, and radiation-sensitive recording material produced with this mixture | CLARIANT GMBH (DE) | 2000-05-16 | — | — | US | disclosed |
| EP-0510446-B1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | CLARIANT GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0510446-A1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |