Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CD74 | P04233 | 1/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SPR | P35270 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735643 | 0.85 | LMNA (0.53) | RAB9AMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL4143936 | 0.83 | PDK1 (0.76) | RAB9ANPC1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL13257726 | 0.79 | RAB9A (0.70) | RAB9AMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL16735666 | 0.78 | LMNA (0.53) | KMT2AALDH1A1LMNATSHRPDK1 | |
| SCHEMBL8133565 | 0.77 | LMNA (0.53) | RAB9AMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL16590061 | 0.76 | ATM (0.65) | L3MBTL1ALDH1A1HPGDPDK1PDK2 | |
| SCHEMBL16590062 | 0.76 | SPR (0.65) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL16589623 | 0.75 | PDK1 (0.80) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL31680509 | 0.75 | HPGD (0.90) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL16060476 | 0.75 | NPC1 (0.68) | RAB9AKMT2ANPC1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044978-A2 | 1-N-alkyl-5'-[(N'-(un)substituted)amido]spiroindolinonaphthoxazines, their preparation, compositions and (co)polymer matrices containing them | Corning S.A. (FR) | 2000-10-18 | — | — | EP | disclosed |
| EP-1038870-A1 | 3,3-bis(aryl)-5-((N-(un)substituted)amido)naphthopyrans, their preparation, compositions and (co)polymer matrices containing them | Corning S.A. (FR) | 2000-09-27 | — | — | EP | disclosed |