Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134482 | 0.87 | FUCA1 (0.36) | MAPTGAAPOLBHIF1AMAPK1 | |
| SCHEMBL8120149 | 0.73 | — | — | |
| SCHEMBL8072013 | 0.69 | ALDH1A1 (0.37) | MAPTGAAPOLBHIF1ALMNA | |
| SCHEMBL8405173 | 0.65 | KDM4E (0.32) | MAPTGAAPOLBHIF1ALMNA | |
| SCHEMBL6721449 | 0.64 | ADORA3 (0.40) | MAPTGAAPOLBHIF1ALMNA | |
| SCHEMBL8133198 | 0.60 | NPSR1 (0.37) | MAPTGAALMNAAKR1C3AKR1C2 | |
| SCHEMBL8128982 | 0.59 | MEN1 (0.32) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL21189286 | 0.59 | NPSR1 (0.38) | MAPTGAAPOLBHIF1AMAPK1 | |
| SCHEMBL21189246 | 0.58 | TSHR (0.43) | MAPTGAALMNATHRBMEN1 | |
| SCHEMBL7749960 | 0.58 | HTR4 (0.64) | GAAMAPK1LMNATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |