Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136338 | 0.90 | — | — | |
| SCHEMBL8130519 | 0.87 | — | — | |
| SCHEMBL9299207 | 0.79 | CYP1A2 (0.37) | CYP1A2CYP2D6CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL7768331 | 0.79 | CYP1A2 (0.37) | CYP1A2CYP2D6CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL7093486 | 0.77 | CYP1A2 (0.33) | CYP1A2CYP2D6CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL8130434 | 0.74 | LMNA (0.35) | CHRNB4CHRNA3 | |
| SCHEMBL7874514 | 0.70 | IDO1 (0.33) | — | |
| SCHEMBL8137223 | 0.69 | TRPV1 (0.34) | TRPV1 | |
| SCHEMBL8137221 | 0.69 | TRPV1 (0.34) | TRPV1 | |
| SCHEMBL8137219 | 0.69 | TRPV1 (0.34) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655448-B1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5977167-A | Benzopyran and benzoxazine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5874446-A | ANTIASTHMATICS, ANTIEPILEPSY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5614633-A | POTASSIUM CHANNEL ACTIVATOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0655448-A1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-31 | — | — | EP | disclosed |