Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395878 | 0.76 | MAPK14 (0.52) | ALDH1A1PTGS1PTGS2MAPK14 | |
| SCHEMBL1521833 | 0.74 | CYP2A6 (0.47) | — | |
| SCHEMBL2231313 | 0.74 | ALDH1A1 (0.47) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL7459057 | 0.74 | RAB9A (0.46) | MEN1ALDH1A1MAPTKMT2APTGS1 | |
| SCHEMBL1521956 | 0.71 | PGR (0.41) | PTGS1 | |
| SCHEMBL5317718 | 0.69 | BCAT2 (0.30) | BCAT2 | |
| SCHEMBL28914110 | 0.69 | NPC1 (0.50) | ALDH1A1MAPTMAPK1KMT2APTGS2 | |
| SCHEMBL28594300 | 0.69 | PTGS2 (0.54) | PTGS1BCAT2PTGS2MAPK14 | |
| SCHEMBL3975326 | 0.69 | PTGS1 (0.37) | PTGS1BCAT2 | |
| SCHEMBL28603928 | 0.69 | PTGS2 (0.54) | PTGS1BCAT2PTGS2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025106-A2 | ALLOSTERIC ADENOSINE RECEPTOR MODULATORS | Medco Research, Inc. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021617-A2 | ALLOSTERIC ADENOSINE RECEPTOR MODULATORS | MEDCO RESEARCH, INC. (US) | 1999-05-06 | — | — | WO | disclosed |