SCHEMBL8147137

SCHEMBL8147137

C=C(C)c1c[c]ccc1C(C)(C)CN=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3602247 0.70
SCHEMBL9404584 0.65 CA2 (0.45)
SCHEMBL11328243 0.63
SCHEMBL27552000 0.63 SHBG (0.34)
SCHEMBL5737958 0.62 NR3C1 (0.33)
SCHEMBL6235866 0.60 CASP3 (0.31)
SCHEMBL6236435 0.60
SCHEMBL3602241 0.60
SCHEMBL29270064 0.59 TAAR1 (0.47)
SCHEMBL8599213 0.59 MAPK1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694532-B1 Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols CIBA SC HOLDING AG (CH) 2000-05-31 EP claimed
EP-0694532-A1 Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols CIBA-GEIGY AG (CH) 1996-01-31 EP claimed
EP-0694532-B1 Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols CIBA SC HOLDING AG (CH) 2000-05-31 EP disclosed
US-5708119-A POLYURETHANES FOR WATERPROOFING AND OIL REPELLENTS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-01-13 US disclosed
US-5693747-A REACTING PERFLUORINATED ALKYLENE OR OXYGEN, SULFUR, NITROGEN INTERRUPTED ALKYLENE SUBSTITUTED EPOXIDE WITH INORGANIC OR ORGANIC SULFUR COMPOUNDS OR ELEMENTAL SULFUR IN PRESENCE OF WATER AND ORGANIC SOLVENT CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-12-02 US disclosed
EP-0694532-A1 Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols CIBA-GEIGY AG (CH) 1996-01-31 EP disclosed