Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781796 | 0.94 | TBXAS1 (0.57) | TBXAS1LTA4HALDH1A1HPGDKDM4E | |
| SCHEMBL3801206 | 0.87 | TBXAS1 (0.60) | TBXAS1LTA4HALDH1A1HPGDMAPT | |
| SCHEMBL7484161 | 0.87 | SMN1; SMN2 (0.62) | TBXAS1LTA4HALDH1A1KDM4ECYP1A2 | |
| SCHEMBL181473 | 0.85 | HPGD (0.61) | TBXAS1ALDH1A1HPGDMAPTGAA | |
| SCHEMBL10726761 | 0.84 | LTA4H (0.57) | TBXAS1LTA4HKDM4ECYP1A2CYP2D6 | |
| SCHEMBL7969106 | 0.84 | TBXAS1 (0.57) | TBXAS1LTA4HALDH1A1HPGDGAA | |
| SCHEMBL9787773 | 0.84 | TBXAS1 (0.57) | TBXAS1LTA4HALDH1A1HPGDGAA | |
| SCHEMBL25378005 | 0.84 | ALDH1A1 (0.57) | LTA4HALDH1A1MAPTGAAKDM4E | |
| SCHEMBL8141712 | 0.84 | GAA (0.62) | TBXAS1ALDH1A1HPGDMAPTGAA | |
| SCHEMBL11566670 | 0.84 | MAPT (0.58) | TBXAS1LTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6041157-A | Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same | GOETZ FREDERICK JAMES (US) | 2000-03-21 | — | — | US | disclosed |