Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484161 | 0.87 | SMN1; SMN2 (0.62) | TBXAS1LTA4HALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3801206 | 0.87 | TBXAS1 (0.60) | TBXAS1LTA4HALDH1A1HPGDGAA | |
| SCHEMBL11985729 | 0.86 | ALDH1A1 (0.56) | TBXAS1ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL181473 | 0.85 | HPGD (0.61) | TBXAS1ALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL8147343 | 0.84 | TBXAS1 (0.57) | TBXAS1LTA4HALDH1A1HPGDGAA | |
| SCHEMBL10726761 | 0.84 | LTA4H (0.57) | TBXAS1LTA4HKDM4ECYP1A2CYP2D6 | |
| SCHEMBL7969106 | 0.84 | TBXAS1 (0.57) | TBXAS1LTA4HALDH1A1HPGDGAA | |
| SCHEMBL6781796 | 0.84 | TBXAS1 (0.57) | TBXAS1LTA4HALDH1A1HPGDKDM4E | |
| SCHEMBL7150227 | 0.84 | ACACB (0.53) | THRAACACBALDH1A1KDM4ECYP1A2 | |
| SCHEMBL27365290 | 0.84 | KMT2A (0.48) | TBXAS1ALDH1A1GAACYP1A2CYP4Z1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |