Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148381 | 0.86 | IARS1 (0.34) | — | |
| SCHEMBL8120553 | 0.85 | MGAM (0.35) | PSMB5MMP1MMP2MMP3MMP9 | |
| SCHEMBL8127269 | 0.81 | PSMB5 (0.32) | PSMB5 | |
| SCHEMBL8127680 | 0.79 | SLC7A5 (0.37) | PSMB5SLC7A5PAX8 | |
| SCHEMBL8130196 | 0.79 | SLC7A5 (0.37) | PSMB5SLC7A5PAX8TSHR | |
| SCHEMBL8127880 | 0.76 | SLC15A1 (0.60) | MMP9SLC15A1TSHR | |
| SCHEMBL8127763 | 0.76 | CTSK (0.36) | PSMB5SLC7A5SLC15A1 | |
| SCHEMBL8129236 | 0.75 | PSMB5 (0.33) | PSMB5SLC7A5SLC15A1 | |
| SCHEMBL8129694 | 0.74 | MGAM (0.34) | TSHR | |
| SCHEMBL8129259 | 0.73 | CTSK (0.44) | SLC15A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |