Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL1982241 | 0.82 | — | — | |
| SCHEMBL27224370 | 0.79 | CHRM1 (0.37) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28216788 | 0.73 | CHRM1 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL27780478 | 0.70 | CA2 (0.39) | TDP1 | |
| SCHEMBL28413616 | 0.66 | CHRM1 (0.34) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL27906526 | 0.65 | HDAC1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL29602658 | 0.65 | HDAC1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1834073 | 0.65 | HDAC1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL5701793 | 0.64 | CHRM1 (0.33) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL27780428 | 0.64 | CA2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155441-A1 | Cosmetic Use of Substituted Amino Heterocylic Carbamoyl Analogs and Related Compounds | AVON PRODUCTS, INC. (US) | 2014-06-05 | — | — | US | claimed |
| WO-2021102113-A1 | SUNSCREEN COMPOSITIONS WITH MULTIPLE PHOTOPROTECTING UV FILTERS | COTY INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20200345013-A1 | ANTI-ADHERENT BOTANICAL COMPOSITIONS | KIMBERLY CLARK CO (US) | 2020-11-05 | — | — | US | disclosed |
| US-10717946-B2 | Water soluble essential oils and their use | Kimberly-Clark Worldside, Inc. (US) | 2020-07-21 | — | — | US | disclosed |
| EP-2516429-B1 | PAXILLIN STIMULATING COMPOSITIONS AND COSMETIC USES THEREOF | AVON PROD INC (US) | 2020-06-24 | — | — | EP | disclosed |
| US-10251831-B2 | Extract for treating wrinkles and/or fine lines | AVON PRODUCTS, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-10195136-B2 | Collagen and elastin stimulating compositions and uses thereof | AVON PRODUCTS, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| EP-2747573-B1 | COLLAGEN AND ELASTIN STIMULATING COMPOSITIONS AND USES THEREOF | AVON PROD INC (US) | 2018-04-18 | — | — | EP | disclosed |
| US-20170367350-A1 | ANTI-ADHERENT BOTANICAL COMPOSITIONS | KIMBERLY CLARK CO (US) | 2017-12-28 | — | — | US | disclosed |
| US-9757327-B2 | Abutilon indicum extracts and methods of use | AVON PRODUCTS, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| WO-2011068595-A1 | TOPICAL COMPOSITIONS CONTAINING DERRIS SCANDENS BENTH. AND A METHOD OF TREATING SKIN | AVON PRODUCTS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |
| US-20110052517-A1 | Cosmetic Uses of Modified Stressed Yeast Extracts and Related Compositions | Avon Place (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2010108098-A1 | COUNTERMEASURE METHODS AND DEVICES | OREGON BIOMEDICAL ENGINEERING INSTITUTE, INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010077396-A1 | TOPICAL COMPOSITIONS CONTAINING MELICOPE HAYESII AND A METHOD OF TREATING SKIN | AVON PRODUCTS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010075004-A1 | TOPICAL COMPOSITIONS CONTAINING CIS-6-NONENOL AND ITS DERIVATIVES AND METHODS FOR TREATING SKIN | AVON PRODUCTS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| US-20100168126-A1 | Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds | AVON PRODUCTS, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168127-A1 | Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds | AVON PRODUCTS, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100166677-A1 | Use of Tiliacora Triandra in Cosmetics and Compositions Thereof | AVON PRODUCTS, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100158828-A1 | Topical Compositions Containing CIS-6-Nonenol and its Derivatives and Methods for Treating Skin | AVON PRODUCTS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-7592024-B1 | Topical compositions containing melicope hayselii and a method of treating skin | AVON PRODUCTS, INC. (US) | 2009-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158828-A1 | Topical Compositions Containing CIS-6-Nonenol and its Derivatives and Methods for Treating Skin | ACSL6, EBP, ELOVL6 | CHRM1 4117/4885AKR1A1 970/4885CHRM3 3956/4885 |
| US-20100168126-A1 | Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds | SIRT2, AADAC, SIRT4 | CHRM1 1307/4885AKR1A1 3023/4885CHRM3 1416/4885 |
| US-20140155441-A1 | Cosmetic Use of Substituted Amino Heterocylic Carbamoyl Analogs and Related Compounds | AADAC, GLA, TYR | CHRM1 3615/4885AKR1A1 3788/4885CHRM3 3913/4885 |
| US-20100168127-A1 | Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds | SIRT2, AADAC, SIRT4 | CHRM1 1307/4885AKR1A1 3023/4885CHRM3 1416/4885 |
| US-10251831-B2 | Extract for treating wrinkles and/or fine lines | LIMS1, CDC42BPG, FN1 | CHRM1 1522/4885AKR1A1 4771/4885CHRM3 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.