Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 12/20 | 0.48 |
| ▸ | HTR1B | P28222 | 12/20 | 0.48 |
| ▸ | HTR1F | P30939 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154553 | 0.89 | NPC1 (0.47) | TP53MAPTHTR1AITKAURKA | |
| SCHEMBL5906202 | 0.85 | HTR1D (0.44) | HTR1DHTR1BHTR1FHTR1ADYRK1A | |
| SCHEMBL8148939 | 0.82 | ULK1 (0.44) | ITKAURKATTKROCK2ROCK1 | |
| SCHEMBL8148201 | 0.81 | ULK1 (0.44) | ITKAURKATTKROCK2ROCK1 | |
| SCHEMBL5315176 | 0.81 | HTR1D (0.69) | HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL3147519 | 0.80 | HTR6 (0.60) | ITKAURKABRD4 | |
| SCHEMBL7481815 | 0.80 | HTR1D (0.76) | MAPTHTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL8146828 | 0.79 | DRD2 (0.43) | MAPT | |
| Hydrochloric Acid SCHEMBL7489449 | 0.79 | HTR1D (0.74) | MAPTHTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL5309846 | 0.79 | HTR1D (0.52) | MAPTHTR1DHTR1BHTR1FHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006173-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |