Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141669 | 0.89 | MAPK1 (0.32) | — | |
| SCHEMBL8150300 | 0.85 | MAPK1 (0.33) | — | |
| SCHEMBL8910755 | 0.84 | TSHR (0.33) | LMNAHSP90AA1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8910147 | 0.81 | LMNA (0.31) | LMNAHSP90AA1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8536552 | 0.81 | GAA (0.32) | LMNAHSP90AA1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8910392 | 0.81 | CCNB2 (0.32) | LMNAMAPTHTT | |
| SCHEMBL8142537 | 0.81 | MYC (0.34) | MAPTHTT | |
| SCHEMBL8155023 | 0.80 | HTT (0.33) | MAPTHTTSMN1; SMN2 | |
| SCHEMBL8156114 | 0.79 | CHRM2 (0.38) | MAPT | |
| SCHEMBL8154324 | 0.79 | LMNA (0.35) | LMNAHSP90AA1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013807-A | Antitumor tetracyclic compounds | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5852204-A | Pyrrolo 3,2-b-!-carbazoles and 1H 1!benzothieno 2,3-f! indoles having anti-tumor activity | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1998-12-22 | — | — | US | disclosed |