Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553056 | 0.89 | DNM1 (0.35) | ALDH1A1MAPK1SMN1; SMN2HPGDLMNA | |
| SCHEMBL8593809 | 0.86 | FBP1 (0.40) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8552707 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL8551609 | 0.83 | EGFR (0.39) | ALDH1A1MAPK1SMN1; SMN2HPGDLMNA | |
| SCHEMBL8555352 | 0.83 | NLRP3 (0.46) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL8550868 | 0.83 | AKR1C3 (0.43) | ALDH1A1MAPK1SMN1; SMN2HPGDLMNA | |
| SCHEMBL8150918 | 0.80 | PDCD1 (0.51) | PDCD1CD274FBP1KDM4EHTT | |
| SCHEMBL8554180 | 0.79 | GLO1 (0.51) | ALDH1A1MAPK1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL8153247 | 0.79 | PDCD1 (0.50) | PDCD1CD274FBP1KDM4EHTT | |
| SCHEMBL8547085 | 0.78 | PDCD1 (0.43) | PDCD1CD274KMT2AFBP1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |