Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835717 | 0.79 | HSD17B10 (0.46) | HSD17B10TSHRADORA2BLMNARGS12 | |
| SCHEMBL11308612 | 0.76 | TSHR (0.38) | HSD17B10TSHRLMNARGS12GAA | |
| SCHEMBL7934703 | 0.75 | HSD17B10 (0.41) | HSD17B10TSHRLMNARGS12GAA | |
| SCHEMBL11628675 | 0.71 | TSHR (0.46) | HSD17B10TSHRLMNARGS12GAA | |
| SCHEMBL3501182 | 0.71 | TSHR (0.44) | HSD17B10TSHRLMNARGS12GAA | |
| SCHEMBL8154208 | 0.70 | ALDH1A1 (0.40) | HSD17B10TSHRLMNARGS12GAA | |
| SCHEMBL2064738 | 0.69 | TSHR (0.42) | HSD17B10TSHRLMNARGS12GAA | |
| SCHEMBL29067975 | 0.68 | TSHR (0.43) | HSD17B10TSHRLMNAGAAMMP2 | |
| SCHEMBL29598045 | 0.68 | TSHR (0.43) | HSD17B10TSHRLMNAGAAMMP2 | |
| SCHEMBL1012052 | 0.68 | TSHR (0.43) | HSD17B10TSHRLMNAGAAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735143-B1 | Process for preparing D-amino acids | TANABE SEIYAKU CO (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5783427-A | DEGRADATION OF LEVOROTATORY STRUCTURE BY TREATMENT WITH MICROORGANISMS SELECTED FROM PROTEUS, PROVIDENCIA, AND YARROWVIA | TANABE SEIYAKU CO., LTD. (JP) | 1998-07-21 | — | — | US | disclosed |
| EP-0735143-A1 | Process for preparing D-amino acids | TANABE SEIYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |