SCHEMBL815713

SCHEMBL815713

Cc1cc(F)cc(I)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 5/20 0.48
PTGS2 P35354 5/20 0.48
TTR P02766 2/20 0.48
CA1 P00915 2/20 0.42
CA2 P00918 1/20 0.42
ALOX5 P09917 2/20 0.41
ALB P02768 1/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
LMNA P02545 3/20 0.37
MEN1 O00255 2/20 0.37
HTT P42858 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
CHEK1 O14757 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929986 0.89 TTR (0.58) PTGS1PTGS2TTRCA1ALOX5
SCHEMBL2058999 0.84 PTGS1 (0.62) PTGS1PTGS2TTRCA1CA2
SCHEMBL815794 0.77 ERN1 (0.46) PTGS1PTGS2TTRCA1ALB
SCHEMBL22133745 0.77 PTGS1 (0.50) PTGS1PTGS2CA1CA2ALOX5
SCHEMBL12023112 0.77 PTGS1 (0.50) PTGS1PTGS2CA1CA2ALOX5
SCHEMBL25882687 0.77 RAPGEF4 (0.31) PTGS1PTGS2
SCHEMBL23907108 0.74 TTR (0.52) TTRCA1CA2ALBLMNA
SCHEMBL7873607 0.74 TTR (0.78) TTRCA1CA2ALBLMNA
SCHEMBL815630 0.74 ALDH1A1 (0.54) PTGS1PTGS2TTRCA1CA2
SCHEMBL14394882 0.73 PTGS1 (0.47) PTGS1PTGS2CA1CA2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595322-B2 Gas-phase biphenylphenol polymerization catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2026-04-07 US disclosed
EP-3925989-B1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-07 EP disclosed
CN-115023445-B Gas-linked phenol polymerization catalyst 陶氏环球技术有限责任公司 2025-03-14 CN disclosed
US-20250034292-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-30 US disclosed
EP-4437011-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 EP disclosed
CN-118302456-A Supported catalyst system containing germanium bridged, anthracenyl substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-07-05 CN disclosed
US-20240150502-A1 BIPHENYLPHENOL POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-09 US disclosed
US-20240052075-A1 BIPHENYLPHENOL POLYMERIZATION CATALYSTS HAVING IMPROVED KINETIC INDUCTION TIMES DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-15 US disclosed
CN-111491942-B Metal-ligand complex, catalyst composition, and method for producing same 沙特基础工业爱思开NEXLENE私人有限公司 2024-01-12 CN disclosed
EP-4291585-A1 BIPHENYLPHENOL POLYMERIZATION CATALYSTS Dow Global Technologies LLC (US) 2023-12-20 EP disclosed
US-20140163186-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2014-06-12 US disclosed
US-8609794-B2 Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES, LLC. (US) 2013-12-17 US disclosed
EP-2491062-B1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-11 EP disclosed
WO-2013101376-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
WO-2013101376-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
CN-102906129-A Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC 2013-01-30 CN disclosed
EP-2491062-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2012-08-29 EP disclosed
WO-2011146291-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 PTGS1 663/4885PTGS2 1249/4885TTR 4757/4885
US-12595322-B2 Gas-phase biphenylphenol polymerization catalysts CCNL2, SCO2, MYB PTGS1 820/4885PTGS2 592/4885TTR 1971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.