Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702725 | 0.79 | LMNA (0.48) | KEAP1NFE2L2EDNRAKMT2AHSD11B1 | |
| SCHEMBL31310995 | 0.78 | CA2 (0.47) | KEAP1NFE2L2KMT2ACA1CA2 | |
| SCHEMBL401308 | 0.78 | CA2 (0.47) | KEAP1NFE2L2KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL19211699 | 0.76 | CA2 (0.45) | KEAP1NFE2L2KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL1017217 | 0.76 | CA2 (0.45) | KEAP1NFE2L2KMT2ACA1CA2 | |
| SCHEMBL11745445 | 0.76 | KEAP1 (0.43) | KEAP1NFE2L2EDNRAKMT2AEDNRB | |
| SCHEMBL9225490 | 0.74 | KDM4E (0.46) | KEAP1NFE2L2KMT2AHSD11B1SLC1A3 | |
| SCHEMBL9228164 | 0.74 | ALDH1A1 (0.50) | KEAP1NFE2L2KMT2ACA9PKM | |
| SCHEMBL6113033 | 0.74 | KMT2A (0.45) | KEAP1NFE2L2EDNRAKMT2ACA1 | |
| SCHEMBL7896751 | 0.73 | KMT2A (0.47) | KEAP1NFE2L2EDNRAKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113698-A | TRPML modulators | 卡斯玛治疗公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |
| US-6051294-A | RETORT-STERILIZABLE PACKAGING MATERIALS EXHIBITING HIGH BARRIER TO OXYGEN | THE DOW CHEMICAL COMPANY (US) | 2000-04-18 | — | — | US | disclosed |
| US-5814373-A | PACKAGING OF OXYGEN SENSITIVE MATERIALS INSIDE A CONTAINER COMPRISING A THERMOPLASTIC POLYMER | DOW CHEMICAL COMPANY (US) | 1998-09-29 | — | — | US | disclosed |