Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800186 | 1.00 | TDP1 (0.44) | TDP1SCN1ASCN2ASCN3AMAPT | |
| SCHEMBL2969544 | 0.90 | TDP1 (0.50) | TDP1SCN1ASCN2ASCN3AMAPT | |
| SCHEMBL5692175 | 0.90 | TDP1 (0.50) | TDP1SCN1ASCN2ASCN3AMAPT | |
| SCHEMBL8458023 | 0.90 | TDP1 (0.50) | TDP1SCN1ASCN2ASCN3AMAPT | |
| SCHEMBL8461979 | 0.73 | RAB9A (0.42) | MAPTKMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8462393 | 0.73 | RAB9A (0.42) | MAPTKMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL1751897 | 0.73 | LMNA (0.48) | TDP1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL636837 | 0.73 | LMNA (0.48) | TDP1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL637664 | 0.73 | LMNA (0.48) | TDP1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15457672 | 0.72 | POLB (0.37) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000319244-A | OPTICALLY ACTIVE AMINO ACID ESTER TARTARIC ACID AMIDE AND ITS PRODUCTION | TORAY IND INC | 2000-11-21 | — | — | JP | disclosed |