Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950454 | 0.76 | KEAP1 (0.47) | MMP12MMEKEAP1PPARGPPARA | |
| SCHEMBL26119143 | 0.75 | NPC1 (0.46) | MEN1KMT2ACYP1A2SLC6A2SLC6A4 | |
| SCHEMBL4135267 | 0.74 | CYP1A2 (0.42) | ANPEPPPARGPPARAACP3CYP1A2 | |
| SCHEMBL3482080 | 0.73 | SLC6A2 (0.40) | ANPEPERAP1MMP12MMEERAP2 | |
| SCHEMBL12630161 | 0.72 | ACE (0.44) | ANPEPERAP1MMP12MMEERAP2 | |
| SCHEMBL8702956 | 0.72 | TP53 (0.47) | MMP12MMEKEAP1MEN1KMT2A | |
| SCHEMBL11648694 | 0.71 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL17891296 | 0.70 | MMP12 (0.43) | MMP12MMEKEAP1PPARGPPARA | |
| SCHEMBL17891302 | 0.69 | MMP12 (0.47) | MMP12MMEKEAP1MEN1KMT2A | |
| SCHEMBL27961561 | 0.68 | TRPA1 (0.48) | MMP12MMEPPARGPPARASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003469-A2 | FRAGRANCE PRECURSORS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2000-05-31 | — | — | EP | disclosed |
| WO-1997030687-A2 | FRAGRANCE PRECURSORS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1997-08-28 | — | — | WO | disclosed |