Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008865 | 0.77 | PIM1 (0.40) | CCNT1PIM1CDK9 | |
| SCHEMBL7507655 | 0.75 | GAA (0.47) | ALDH1A1MAPTNPSR1HPGDTSHR | |
| SCHEMBL7005539 | 0.72 | CDK4 (0.55) | ALDH1A1MAPTHPGDTSHRHSD17B10 | |
| SCHEMBL7005313 | 0.72 | PKM (0.40) | ALDH1A1MAPTNPSR1HPGDGAA | |
| SCHEMBL7005879 | 0.70 | PIM1 (0.48) | MAPTTSHRHSD17B10SMN1; SMN2MEN1 | |
| Acetic Acid SCHEMBL7011660 | 0.68 | CAMK2D (0.46) | MAPTTSHRHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL7010209 | 0.68 | PIM1 (0.37) | MAPTTSHRHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL7008320 | 0.67 | RPS6KB1 (0.41) | ALDH1A1MAPTTSHRGAANPC1 | |
| SCHEMBL6379635 | 0.67 | NR4A2 (0.69) | ALDH1A1MAPTNPSR1TSHRKDM4E | |
| SCHEMBL8159849 | 0.67 | AHR (0.41) | ALDH1A1MAPTNPSR1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042317-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032483-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 1999-07-01 | — | — | WO | disclosed |