Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 1.00 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tolnaftate SCHEMBL3520 | 1.00 | LMNA (1.00) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL29484221 | 1.00 | LMNA (1.00) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL30382951 | 1.00 | LMNA (1.00) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL28341077 | 0.99 | LMNA (0.97) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL10897084 | 0.99 | LMNA (0.97) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL22227756 | 0.99 | LMNA (0.97) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL8985002 | 0.95 | LMNA (0.90) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL8609283 | 0.94 | LMNA (0.88) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL15568032 | 0.94 | MAPT (0.88) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL893162 | 0.94 | LMNA (0.88) | LMNAMAPTTDP1NR1I2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032263-A1 | SURFACTANT-BASED ANTIMICROBIAL COMPOSITIONS AND METHODS FOR USING SAME | Woodward Laboratories Inc. (US) | 2000-09-06 | — | — | EP | disclosed |
| US-6087400-A | MIXTURE CONTAINING BENZALKONIUM CHLORIDE AND WATER | WOODWARD LABORATORIES, INC. (US) | 2000-07-11 | — | — | US | disclosed |
| US-6013677-A | APPLYING TO THE NAIL A NON-AQUEOUS ANTIMICROBIAL NAIL COATING CONTAINING A FILM FORMING POLYMER, AN ORGANIC SOLVENT, A ANTIMICROBIAL AGENT COMPRISING SOLUBILZED BENZALKONIUM CHLORIDE AND CAPABLE OF LEACHING FROM NAIL COATING | WOODWARD LABORATORIES, INC. (US) | 2000-01-11 | — | — | US | disclosed |
| US-5994383-A | MIXTURE CONTAINING BENZALKONIUM CHLORIDE AND WATER | WOODWARD LABORATORIES, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1999036033-A1 | ANTIMICROBIAL NAIL COATING COMPOSITION | WOODWARD LABORATORIES, INC. (US) | 1999-07-22 | — | — | WO | disclosed |
| WO-1999025190-A1 | SURFACTANT-BASED ANTIMICROBIAL COMPOSITIONS AND METHODS FOR USING SAME | WOODWARD LABORATORIES, INC. (US) | 1999-05-27 | — | — | WO | disclosed |