Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 1.00 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tolnaftate SCHEMBL8160019 | 1.00 | LMNA (1.00) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL30382951 | 1.00 | LMNA (1.00) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL3520 | 1.00 | LMNA (1.00) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL10897084 | 0.99 | LMNA (0.97) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL22227756 | 0.99 | LMNA (0.97) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL28341077 | 0.99 | LMNA (0.97) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL8985002 | 0.95 | LMNA (0.90) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL8609283 | 0.94 | LMNA (0.88) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL15568032 | 0.94 | MAPT (0.88) | LMNAMAPTTDP1NR1I2CYP1A2 | |
| Tolnaftate SCHEMBL893162 | 0.94 | LMNA (0.88) | LMNAMAPTTDP1NR1I2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-3876949-B1 | DERMAL SKIN PROTECTANT AND CARRIER | INSPIRED MAT STRATEGIES LLC (US) | 2025-08-20 | — | — | EP | claimed |
| EP-4069690-B1 | POLYMORPHS OF TRIAZOLE ANTIFUNGAL COMPOUND PC945 | PULMOCIDE LTD (GB) | 2024-11-13 | — | — | EP | claimed |
| EP-3529359-B1 | TUMOR INFILTRATING LYMPHOCYTES FOR USE IN THERAPY | UNIV MINNESOTA (US) | 2023-12-13 | — | — | EP | claimed |
| EP-2916820-B1 | DELIVERY OF BIOLOGICALLY-ACTIVE AGENTS USING VOLATILE, HYDROPHOBIC SOLVENTS | ROCHAL TECH LLC (US) | 2023-10-11 | — | — | EP | claimed |
| EP-3139939-B1 | COMPOSITIONS AND METHODS FOR TREATING SKIN AND MUCOUS MEMBRANE DISEASES | UNIV CALIFORNIA (US) | 2023-09-06 | — | — | EP | claimed |
| EP-2640393-B1 | CBP/CATENIN ANTAGONISTS FOR ENHANCING ASYMMETRIC DIVISION OF SOMATIC STEM CELLS | UNIV SOUTHERN CALIFORNIA (US) | 2022-10-12 | — | — | EP | claimed |
| US-12508252-B2 | Compositions and methods for pain relief and numbing | RELIEVE THERAPEUTICS PTE. LTD. (SG) | 2025-12-30 | — | — | US | disclosed |
| US-12478747-B2 | Aerosol delivery device and operating method for the aerosol delivery device | PARI PHARMA GMBH (DE) | 2025-11-25 | — | — | US | disclosed |
| EP-4631628-A2 | AEROSOL GENERATOR | PARI Pharma GmbH (DE) | 2025-10-15 | — | — | EP | disclosed |
| EP-4230243-B1 | METHOD OF MANUFACTURING A VIBRATABLE MEMBRANE FOR USE IN AN AEROSOL GENERATOR | PARI PHARMA GMBH (DE) | 2025-10-01 | — | — | EP | disclosed |
| US-12151033-B2 | Foam compositions, foam matrices and methods | COVALON TECHNOLOGIES INC. (CA) | 2024-11-26 | — | — | US | disclosed |
| EP-4438088-A2 | AEROSOL DELIVERY DEVICE AND OPERATING METHOD FOR THE AEROSOL DELIVERY DEVICE | PARI Pharma GmbH (DE) | 2024-10-02 | — | — | EP | disclosed |
| EP-2968680-B1 | SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION | C P MEDICAL CORP (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20230119086-A1 | AEROSOL DELIVERY DEVICE AND OPERATING METHOD FOR THE AEROSOL DELIVERY DEVICE | PARI PHARMA GMBH (DE) | 2023-04-20 | — | — | US | disclosed |
| US-11596710-B2 | Biocompatible hydrogel treatments for retinal detachment | AQUARIAN CREDIT FUNDING LLC | 2023-03-07 | — | — | US | disclosed |
| US-11547822-B2 | Aerosol delivery device and operating method for the aerosol delivery device | PARI PHARMA GMBH (DE) | 2023-01-10 | — | — | US | disclosed |
| EP-4093812-A1 | BIODEGRADABLE COMPOSITIONS AND ARTICLES MADE FROM CELLULOSE ACETATE | Eastman Chemical Company (US) | 2022-11-30 | — | — | EP | disclosed |
| US-20220160689-A1 | COMPOSITIONS AND METHODS FOR PAIN RELIEF AND NUMBING | Ziropa, Inc. (US) | 2022-05-26 | — | — | US | disclosed |
| US-20220088630-A1 | AEROSOL GENERATOR | PARI PHARMA GMBH (DE) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12508252-B2 | Compositions and methods for pain relief and numbing | PRPH, PMP22, RBM25 | LMNA 760/4885MAPT 274/4885TDP1 384/4885 |
| US-11596710-B2 | Biocompatible hydrogel treatments for retinal detachment | ALDH1A2, RB1, UACA | LMNA 615/4885MAPT 3051/4885TDP1 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.