Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839338 | 0.85 | CACNA1F (0.44) | LMNAKMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL7845341 | 0.81 | ELANE (0.37) | LMNAKMT2AMEN1L3MBTL1ELANE | |
| Hydrochloric Acid SCHEMBL7832311 | 0.79 | SSTR4 (0.50) | SSTR4LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL7841384 | 0.75 | SSTR4 (0.50) | SSTR4KMT2AMEN1SSTR1POLB | |
| Hydrochloric Acid SCHEMBL7831467 | 0.74 | SSTR4 (0.49) | SSTR4KMT2AMEN1SSTR1POLB | |
| SCHEMBL6190022 | 0.73 | L3MBTL1 (0.60) | SSTR4LMNAKMT2AMEN1L3MBTL1 | |
| M-Xylene SCHEMBL25415321 | 0.72 | L3MBTL1 (0.51) | LMNAKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL962133 | 0.71 | OPRM1 (0.62) | LMNAKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL7840407 | 0.71 | OPRD1 (0.48) | SSTR4LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL13278520 | 0.69 | OPRM1 (0.51) | LMNAKMT2AMEN1OPRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944388-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0944388-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1997038665-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | disclosed |