Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | BLM | P54132 | 6/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | NSD2 | O96028 | 3/20 | 0.66 |
| ▸ | PLEC | Q15149 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 2/20 | 0.66 |
| ▸ | APAF1 | O14727 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 2/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | CASP7 | P55210 | 2/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.66 |
| ▸ | TDP2 | O95551 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | GALK1 | P51570 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167880 | 0.90 | KDM4E (0.77) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL8164257 | 0.78 | KDM4E (0.63) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL8147117 | 0.78 | KDM4E (0.75) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL8168066 | 0.78 | ALDH1A1 (0.53) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL8164218 | 0.72 | LMNA (0.50) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL8164223 | 0.71 | ALDH1A1 (0.55) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL4787894 | 0.67 | KDM4E (0.68) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL4787299 | 0.66 | KDM4E (0.72) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL15032605 | 0.66 | SAE1 (0.76) | KDM4EMAPTMEN1KMT2ABLM | |
| SCHEMBL15032610 | 0.66 | SAE1 (0.72) | KDM4EMAPTMEN1KMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |