Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154609 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL4163347 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL28771911 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1312119 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4E | |
| SCHEMBL14156178 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8099706 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4ETSHR | |
| SCHEMBL965776 | 0.74 | POLB (0.35) | ALDH1A1KDM4ETSHR | |
| SCHEMBL8913308 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL1311698 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4E | |
| SCHEMBL14156046 | 0.73 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288652-B1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO KG (DE) | 2012-09-19 | — | — | EP | claimed |
| US-20110272628-A1 | Preparation For Initiating Radical Reactions | UNITED INITIATORS GMBH (DE) | 2011-11-10 | — | — | US | claimed |
| EP-2288652-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | United Initiators GmbH & Co. KG (DE) | 2011-03-02 | — | — | EP | claimed |
| WO-2009146916-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO. KG (DE) | 2009-12-10 | — | — | WO | claimed |
| EP-2130858-A1 | Preparations to initiate radical reactions | Degussa Initiators GmbH & Co. KG (DE) | 2009-12-09 | — | — | EP | claimed |
| US-20180208566-A1 | Deuterated Meclizine | CONCERT PHARMACEUTICALS, INC. | 2018-07-26 | — | — | US | disclosed |
| US-20180134716-A1 | COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION | MILLENNIUM PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | disclosed |
| US-20180072671-A1 | INHIBITORS OF HISTONE DEACETYLASE | THE BROAD INSTITUTE, INC. (US) | 2018-03-15 | — | — | US | disclosed |
| US-9790184-B2 | Inhibitors of histone deacetylase | THE BROAD INSTITUTE, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-9765078-B2 | Compounds and methods for inhibiting mitotic progression | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170107174-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND THEIR USE IN TREATING NEURODEGENERATIVE DISEASES | UNIVERSITE DE LILLE (FR) | 2017-04-20 | — | — | US | disclosed |
| US-20160185782-A1 | COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION | MILLENNIUM PHARMACEUTICALS, INC. | 2016-06-30 | — | — | US | disclosed |
| US-20090299060-A1 | COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090264525-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| US-7572784-B2 | Compounds and methods for inhibiting mitotic progression | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-20090197201-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-06 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080200465-A1 | Substituted with a morpholine group through amido heterocylic groups; interfering with the expression of genes essential for the pathogen's proliferation; treating viral and protozoan infections in mammals | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-7348427-B2 | Antipathogenic benzamide compounds | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20070185087-A1 | Compounds and methods for inhibiting mitotic progression | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200465-A1 | Substituted with a morpholine group through amido heterocylic groups; interfering with the expression of genes essential for the pathogen's proliferation; treating viral and protozoan infections in mammals | IRF3, BCL3, L3MBTL3 | ALDH1A1 3117/4885KDM4E 1943/4885TSHR 1107/4885 |
| US-20070185087-A1 | Compounds and methods for inhibiting mitotic progression | AURKC, AURKA, AURKB | ALDH1A1 3815/4885KDM4E 774/4885TSHR 4809/4885 |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | ALDH1A1 4330/4885KDM4E 4805/4885TSHR 594/4885 |
| US-20170107174-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND THEIR USE IN TREATING NEURODEGENERATIVE DISEASES | MAPT, PSEN2, SNCA | ALDH1A1 1189/4885KDM4E 4092/4885TSHR 4804/4885 |
| US-20180072671-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC3, HDAC1, HDAC11 | ALDH1A1 1955/4885KDM4E 353/4885TSHR 4164/4885 |
| US-20180134716-A1 | COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION | AURKC, AURKA, AURKB | ALDH1A1 3815/4885KDM4E 774/4885TSHR 4809/4885 |
| US-20180208566-A1 | Deuterated Meclizine | FGFR3, FGFR1, FGFR2 | ALDH1A1 2118/4885KDM4E 3313/4885TSHR 461/4885 |
| US-20090299060-A1 | COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION | AURKC, AURKA, AURKB | ALDH1A1 3815/4885KDM4E 774/4885TSHR 4809/4885 |
| US-20090264525-A1 | FLUOROSURFACTANTS | FASN, FFAR3, SGMS2 | ALDH1A1 2925/4885KDM4E 4460/4885TSHR 754/4885 |
| US-20160185782-A1 | COMPOUNDS AND METHODS FOR INHIBITING MITOTIC PROGRESSION | AURKC, AURKA, AURKB | ALDH1A1 3815/4885KDM4E 774/4885TSHR 4809/4885 |
| US-20090197201-A1 | FLUOROSURFACTANTS | CBR3, SCO2, FPR3 | ALDH1A1 3874/4885KDM4E 3873/4885TSHR 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.