Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8167198 | 0.80 | TSHR (0.36) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL2135868 | 0.78 | PNMT (0.32) | — | |
| Fluoride Ion SCHEMBL3470296 | 0.76 | PNMT (0.32) | — | |
| Hydrochloric Acid SCHEMBL3894866 | 0.74 | PNMT (0.33) | — | |
| Hydrochloric Acid SCHEMBL8170585 | 0.70 | PGR (0.35) | — | |
| Hydrochloric Acid SCHEMBL978987 | 0.68 | NPC1 (0.36) | CYP1A2 | |
| SCHEMBL8161783 | 0.68 | PNMT (0.32) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9066343 | 0.68 | PNMT (0.32) | — | |
| Hydrochloric Acid SCHEMBL8159955 | 0.65 | PGR (0.33) | — | |
| Hydrochloric Acid SCHEMBL2143359 | 0.64 | PGR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000313713-A | PRODUCTION OF POLYOLEFIN HAVING WIDE MOLECULAR WEIGHT DISTRIBUTION | ELANAC GMBH | 2000-11-14 | — | — | JP | disclosed |