SCHEMBL816740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL816917	0.93	LIPG (0.46)	LIPGCYP3A4CYP2D6CYP2C9KDM4E
	SCHEMBL816432	0.89	LIPG (0.47)	LIPGCYP3A4CYP2D6CYP2C9PTGS2
	SCHEMBL814544	0.89	LIPG (0.43)	LIPGCYP3A4CYP2D6CYP2C9KDM4E
	SCHEMBL818080	0.88	LIPG (0.50)	LIPGCYP3A4CYP2D6CYP2C9CYSLTR2
	SCHEMBL815976	0.87	KDM4E (0.41)	LIPGCYP3A4KDM4EMEN1RECQL
	SCHEMBL3081308	0.82	LIPG (0.56)	LIPGPTGS2CYSLTR2CYSLTR1
	SCHEMBL815454	0.82	LIPG (0.56)	LIPGPTGS2CYSLTR2CYSLTR1
	SCHEMBL816634	0.82	LIPG (0.40)	LIPGCYP3A4CYP2D6CYP2C9KDM4E
	SCHEMBL816997	0.82	TSHR (0.42)	LIPGCYP3A4HTTTSHRCES2
	SCHEMBL817377	0.81	ALDH1A1 (0.38)	LIPGIAPPHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.