Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167588 | 0.83 | LMNA (0.53) | PTGER1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL9054578 | 0.83 | KDM4E (0.55) | TDP1L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL410077 | 0.80 | PTGER1 (0.76) | PTGER1TDP1L3MBTL1MAPTEDNRA | |
| SCHEMBL5778363 | 0.79 | GAA (0.56) | PTGER1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL6358805 | 0.76 | SGMS2 (0.61) | PTGER1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL8697604 | 0.75 | USP28 (0.59) | PTGER1LMNAALDH1A1CTSVCTSL | |
| SCHEMBL5305401 | 0.75 | LMNA (0.60) | PTGER1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL27428219 | 0.75 | GAA (0.50) | PTGER1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL4345493 | 0.74 | GAA (0.60) | TDP1L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL4355825 | 0.74 | MAPT (0.60) | TDP1L3MBTL1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773930-B1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LTD (GB) | 2000-10-11 | — | — | EP | disclosed |