Hydrochloric Acid

Hydrochloric Acid

SCHEMBL816979

[Cl-].[Cl-].c1ccc2c(c1)-c1ccccc1C2[Hf+2]C1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.34
CHRM2 known ✓ P08172 1/20 0.34
CHRM1 known ✓ P11229 1/20 0.34
SLC6A2 known ✓ P23975 1/20 0.34
SLC6A3 known ✓ Q01959 1/20 0.34
GPR3 P46089 2/20 0.42
HTR2A P28223 2/20 0.42
CYP19A1 P11511 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
POLB P06746 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
BCHE P06276 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL6910966 0.95 GPR3 (0.39) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL8379133 0.94 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL8701791 0.90 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL7940445 0.83 ALDH1A1 (0.38) GPR3HTR2ACYP19A1CYP2D6MAPT
Hydrochloric Acid SCHEMBL6919020 0.78 LMNA (0.39) GPR3POLBMAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL5358538 0.77 MYC (0.37) GPR3HTR2AACHEKMT2AMEN1
Hydrochloric Acid SCHEMBL5347365 0.77 GPR3 (0.35) GPR3HTR2AACHEKMT2AMEN1
Hydrochloric Acid SCHEMBL6918930 0.76 HTR6 (0.33) GPR3HTR2ACYP2D6CHRM2CHRM1
Ethylene SCHEMBL4326783 0.74 GPR3 (0.32) GPR3
Hydrochloric Acid SCHEMBL30854875 0.74 GPR3 (0.40) GPR3HTR2ACYP19A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8633125-B2 Catalyst composition for preparation of polyethylene BASELL POLYOLEFINE GMBH (DE) 2014-01-21 US claimed
US-12415911-B2 Polyethylene composition for filaments or fibers BASELL POLYOLEFINE GMBH (DE) 2025-09-16 US disclosed
US-11999839-B2 Polyethylene composition for filaments or fibers BASELL POLYOLEFINE GMBH (DE) 2024-06-04 US disclosed
EP-4069775-B1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2024-04-03 EP disclosed
EP-4069774-B1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2024-01-17 EP disclosed
US-20230075830-A1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2023-03-09 US disclosed
US-20230002598-A1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2023-01-05 US disclosed
WO-2021110769-A1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2021-06-10 WO disclosed
WO-2021110762-A1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2021-06-10 WO disclosed
EP-2673315-B1 POLYETHYLENE FILMS EQUISTAR CHEM LP (US) 2019-03-20 EP disclosed
EP-0996647-A1 PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION BOREALIS A/S (DK) 2000-05-03 EP disclosed
EP-0991676-A1 MULTISTAGE POLYMERIZATION PROCESS USING A CATALYST HAVING DIFFERENT CATALYTICALLY ACTIVE SITES BOREALIS A/S (DK) 2000-04-12 EP disclosed
CN-1049899-C Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 2000-03-01 CN disclosed
US-5916982-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1999-06-29 US disclosed
WO-1999021895-A1 PROCESS BOREALIS A/S (DK) 1999-05-06 WO disclosed
WO-1999003897-A1 PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION BOREALIS A/S (DK) 1999-01-28 WO disclosed
WO-1998057998-A1 MULTISTAGE POLYMERIZATION PROCESS USING A CATALYST HAVING DIFFERENT CATALYTICALLY ACTIVE SITES BOREALIS A/S (DK) 1998-12-23 WO disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0768319-A1 Process for the production of polyolefins NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
CN-1128272-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1996-08-07 CN disclosed