Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953102 | 0.90 | METAP1 (0.39) | ALDH1A1HPGDMAPTMAPK1HSD17B10 | |
| SCHEMBL5951356 | 0.88 | GABRG2 (0.45) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL5953322 | 0.79 | HTR7 (0.43) | ALDH1A1HPGDBRD4MAPTCYP19A1 | |
| SCHEMBL5951404 | 0.77 | ACHE (0.42) | HTR2CGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL5951762 | 0.75 | ACHE (0.51) | MAOAALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL5951903 | 0.72 | ACHE (0.54) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL5951906 | 0.70 | METAP1 (0.44) | CYP19A1 | |
| SCHEMBL5953305 | 0.70 | HTR7 (0.44) | HTR2CALDH1A1HPGDMAPTCYP19A1 | |
| SCHEMBL28067083 | 0.69 | KDM4E (0.50) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL5951085 | 0.69 | ALDH1A1 (0.41) | GABRG2GABRB3GABRA5GABRA1GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968158-A1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | Basell Polyolefine GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040331-A1 | PREPARATION OF PREPARING SUBSTITUTED INDANONES | TARGOR GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |