SCHEMBL8171973

SCHEMBL8171973

C=CCOc1ccc(CC=C)c(C)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
HPGD P15428 5/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
P2RY12 Q9H244 1/20 0.39
TSHR P16473 3/20 0.37
HSD17B10 Q99714 2/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
GAA P10253 1/20 0.36
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
MAPK1 P28482 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5806322 0.87 HPGD (0.51) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL5196483 0.84 ALDH1A1 (0.46) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL11221012 0.79 ALDH1A1 (0.47) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL11639066 0.79 KDM4E (0.37) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL29108659 0.78 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL22701017 0.77 L3MBTL1 (0.54) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL22701018 0.77 MAPT (0.43) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL5194222 0.77 ALDH1A1 (0.43) ALDH1A1HPGDKDM4EMAPTMEN1
SCHEMBL9768377 0.75 ADRA2A (0.50) ALDH1A1HPGDKDM4EMAPTTSHR
SCHEMBL4780536 0.74 HPGD (0.46) ALDH1A1HPGDKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000055226-A1 ALLYL COMPOUNDS, COMPOSITIONS CONTAINING ALLYL COMPOUNDS AND PROCESSES FOR FORMING AND CURING POLYMER COMPOSITIONS HERCULES INCORPORATED (US) 2000-09-21 WO claimed