Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618007 | 0.79 | EPHX1 (0.34) | KEAP1NFE2L2CES2CES1 | |
| SCHEMBL479255 | 0.79 | EPHX1 (0.34) | KEAP1NFE2L2CES2CES1 | |
| SCHEMBL7618010 | 0.79 | EPHX1 (0.34) | KEAP1NFE2L2CES2CES1 | |
| SCHEMBL10815498 | 0.79 | EPHX1 (0.34) | KEAP1NFE2L2CES2CES1 | |
| SCHEMBL7711598 | 0.75 | TSHR (0.39) | HTTNPC1GAASMN1; SMN2 | |
| SCHEMBL701590 | 0.65 | EPHX1 (0.37) | KEAP1NFE2L2 | |
| SCHEMBL3871375 | 0.65 | EPHX1 (0.37) | KEAP1NFE2L2 | |
| SCHEMBL15673252 | 0.65 | GRIK1 (0.47) | CES2CES1HTTNPC1GAA | |
| SCHEMBL8395889 | 0.65 | CES2 (0.36) | KEAP1NFE2L2CES2CES1NPC1 | |
| SCHEMBL5339681 | 0.65 | KEAP1 (0.39) | KEAP1NFE2L2CES2CES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030747-A | CHEMICALLY AMPLIFIED RESIST CONSISTS OF A PHOTOACID GENERATOR, A CROSSLINKING AGENT ACTIVATED IN PRESENCE OF ACID AND A COPOLYMER OF ACRYLIC OR METHACRYLIC ESTER CONTAINING AN ACID, HYDROXY OR ESTER POLAR GROUP AND A COMPOUND | NEC CORPORATION (JP) | 2000-02-29 | — | — | US | disclosed |