Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178561 | 0.86 | MPO (0.41) | PRKAA2ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL8173521 | 0.80 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BTSHRHCRTR2 | |
| SCHEMBL8174924 | 0.73 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BHCRTR2 | |
| SCHEMBL8174317 | 0.71 | USP7 (0.40) | PRKAA2TSHRLMNAALOX15MAPK1 | |
| SCHEMBL8174233 | 0.70 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BTSHRLMNA | |
| SCHEMBL8167612 | 0.68 | GCGR (0.40) | TSHRNPC1RAB9AGCGRPOLB | |
| SCHEMBL8174451 | 0.67 | ADRA1D (0.52) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8179453 | 0.66 | ADRA1D (0.39) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8173485 | 0.66 | ADRA1D (0.51) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8174322 | 0.66 | USP7 (0.39) | PRKAA2TSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090825-A | Oxazole derivatives as antagonists of alpha 1C andrenergic receptors | GLAXO WELLCOME INC. (US) | 2000-07-18 | — | — | US | disclosed |