Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174185 | 0.90 | LMNA (0.45) | ADRA1DADRA1AADRA1BLMNATSHR | |
| SCHEMBL8166794 | 0.87 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BLMNATSHR | |
| SCHEMBL8174924 | 0.80 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BHCRTR2KCNH2 | |
| SCHEMBL8178641 | 0.79 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BHCRTR2LMNA | |
| SCHEMBL8174265 | 0.78 | HCRTR2 (0.42) | HCRTR2LMNAALOX15MAPK1MAPT | |
| SCHEMBL8173512 | 0.77 | HTR2B (0.46) | HCRTR2LMNAALOX15MAPK1TUBB4A | |
| SCHEMBL8174249 | 0.72 | ADRA1D (0.84) | ADRA1DADRA1AADRA1BCDK9 | |
| SCHEMBL8174657 | 0.70 | PRKAA2 (0.41) | ADRA1DADRA1AADRA1BHCRTR2LMNA | |
| SCHEMBL3092492 | 0.70 | FAAH (0.51) | LMNAMAPK11MAPK14TUBB4ATUBB | |
| SCHEMBL3102619 | 0.70 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090825-A | Oxazole derivatives as antagonists of alpha 1C andrenergic receptors | GLAXO WELLCOME INC. (US) | 2000-07-18 | — | — | US | disclosed |