SCHEMBL817509

SCHEMBL817509

C=C/C(=C/C(=O)C[C@H](C)C[C@@H](C)CC[C@H](O)[C@H](C)C(=O)C[C@@H](O)[C@H](C)[C@@H](C)OC(=O)C[C@@H](O)C1=C(C)C(=O)OC1=O)CC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPP2CA P67775 7/20 1.00
PPP5C P53041 2/20 1.00
ALDH1A1 P00352 1/20 1.00
THRB P10828 1/20 1.00
HPGD P15428 1/20 1.00
PPP1CC P36873 1/20 1.00
PTPN11 Q06124 2/20 0.88
PTPA Q15257 2/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15445020 1.00 PPP2CA (1.00) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15381941 0.92 PPP2CA (0.90) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15382081 0.92 PPP2CA (1.00) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL889228 0.88 PPP2CA (0.80) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15381936 0.86 PPP2CA (0.86) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15381939 0.84 PPP2CA (0.90) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15381940 0.84 PPP2CA (0.90) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15444945 0.84 PPP2CA (0.90) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15444944 0.84 PPP2CA (0.90) PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15445017 0.83 PPP2CA (1.00) PPP2CAPPP5CALDH1A1THRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673458-A1 METHODS OF ENHANCING PRODUCTION OF METABOLITES IN BACTERIA JOHN INNES CENTRE (GB) 2026-01-07 EP claimed
EP-3966344-B1 KINASE SCREENING ASSAYS UNIV NEWCASTLE (GB) 2025-06-25 EP claimed
WO-2024180095-A1 METHODS OF ENHANCING PRODUCTION OF METABOLITES IN BACTERIA JOHN INNES CENTRE (GB) 2024-09-06 WO claimed
US-20220213524-A1 KINASE SCREENING ASSAYS THE UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2022-07-07 US claimed
EP-3966344-A1 KINASE SCREENING ASSAYS University of Newcastle Upon Tyne (GB) 2022-03-16 EP claimed
WO-2020225535-A1 KINASE SCREENING ASSAYS UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2020-11-12 WO claimed
US-20150352131-A1 Compositions and Methods for the Prevention and Treatment of Osteolysis and Osteoporosis RHODE ISLAND HOSPITAL (US) 2015-12-10 US claimed
US-20150038432-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RETINAL DEGENERATION UNIVERSITE DE STRASBOURG (FR) 2015-02-05 US claimed
EP-2817020-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RETINAL DEGENERATION Université de Strasbourg (FR) 2014-12-31 EP claimed
WO-2014113584-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF OSTEOLYSIS AND OSTEOPOROSIS RHODE ISLAND HOSPITAL (US) 2014-07-24 WO claimed
US-20110281942-A1 Tautomycetin and Tautomycetin Analog Biosynthesis WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-11-17 US claimed
WO-2007102685-A1 NOUA NOVEL IN VIVO PERFUSION METHOD FOR INDUCING DIFFERENTIAL SIGNALING IN AN ANIMAL INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2007-09-13 WO claimed
WO-2007015175-A2 USE OF PP-1 INHIBITORS TO PREVENT MISSPLICING EVENTS Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2007-02-08 WO claimed
EP-1736154-A1 Use of PP-1 inhibitors to prevent missplicing events Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2006-12-27 EP claimed
US-20060148060-A1 Biomolecule transduction motif Mph-1-BTM and the use thereof FORHUMANTECH. CO., LTD. (KR) 2006-07-06 US claimed
WO-2005118797-A2 BIOSYNTHETIC GENE CLUSTER FOR TAUTOMYCETIN KOSAN BIOSCIENCES INCORPORATED (US) 2005-12-15 WO claimed
US-6608045-B2 Suppresses the expression of interleukin-2 CHONG KUN DANG CORPORATION (KR) 2003-08-19 US claimed
US-20030073737-A1 Tolerance induction COOKE NIGEL GRAHAM (CH) 2003-04-17 US claimed
US-20010016599-A1 STREPTOMYCES SP PRODUCING TAUTOMYCETIN AND IMMUNOSUPPRESSANT COMPRISING TAUTOMYCETIN AS ACTIVE INGREDIENT CHONG KUN DANG CORPORATION (KR) 2001-08-23 US claimed
WO-1999050388-A1 STREPTOMYCES SP. PRODUCING TAUTOMYCETIN AND IMMUNOSUPPRESSANT COMPRISING TAUTOMYCETIN AS ACTIVE INGREDIENT CHONG KUN DANG CORPORATION (KR) 1999-10-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073737-A1 Tolerance induction HLA-DRB1, HLA-C, CD14 PPP2CA 175/4885PPP5C 478/4885ALDH1A1 2969/4885
US-20110281942-A1 Tautomycetin and Tautomycetin Analog Biosynthesis PTPRJ, PPP5C, MTMR1 PPP2CA 20/4885PPP5C 2/4885ALDH1A1 2934/4885
US-20010016599-A1 STREPTOMYCES SP PRODUCING TAUTOMYCETIN AND IMMUNOSUPPRESSANT COMPRISING TAUTOMYCETIN AS ACTIVE INGREDIENT CD69, IL2RA, IL2 PPP2CA 2333/4885PPP5C 3339/4885ALDH1A1 3058/4885
US-20150352131-A1 Compositions and Methods for the Prevention and Treatment of Osteolysis and Osteoporosis SOST, PTPN6, PTPN3 PPP2CA 138/4885PPP5C 105/4885ALDH1A1 4885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.