Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808706 | 1.00 | MMP12 (0.49) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL7693929 | 0.84 | MMP12 (0.49) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL7693931 | 0.84 | MMP12 (0.49) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL4306985 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2AMEN1POLB | |
| SCHEMBL7279889 | 0.78 | MMP12 (0.68) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL7267577 | 0.78 | BLM (0.39) | ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL5962212 | 0.77 | SMN1; SMN2 (0.45) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL1532473 | 0.77 | MMP12 (0.54) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL2939724 | 0.77 | MMP12 (0.54) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL5962211 | 0.76 | MMP12 (0.42) | MMP12ALDH1A1TSHRSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742143-B2 | Process for the preparation of prostaglandin analogues | SCINOPHARM TAIWAN, LTD. (TW) | 2014-06-03 | — | — | US | disclosed |
| US-8742143-B2 | Process for the preparation of prostaglandin analogues | SCINOPHARM TAIWAN, LTD. (TW) | 2014-06-03 | — | — | US | disclosed |
| US-20130211128-A1 | Process for the Preparation of Prostaglandin Analogues | SCINOPHARM TAIWAN LTD. (TW) | 2013-08-15 | — | — | US | disclosed |
| US-20130211128-A1 | Process for the Preparation of Prostaglandin Analogues | SCINOPHARM TAIWAN LTD. (TW) | 2013-08-15 | — | — | US | disclosed |
| US-8436194-B2 | Process for the preparation of prostaglandin analogues and intermediates thereof | SCINOPHARM TAIWAN, LTD. (TW) | 2013-05-07 | — | — | US | disclosed |
| US-20110130577-A1 | Process for the Preparation of Prostaglandin Analogues and Intermediates Thereof | SCINOPHARM TAIWAN LTD. | 2011-06-02 | — | — | US | disclosed |
| US-20110130577-A1 | Process for the Preparation of Prostaglandin Analogues and Intermediates Thereof | SCINOPHARM TAIWAN LTD. | 2011-06-02 | — | — | US | disclosed |
| US-7897795-B2 | Process for the preparation of prostaglandin analogues and intermediates thereof | SCINOPHARM TAIWAN LTD. (TW) | 2011-03-01 | — | — | US | disclosed |
| US-20090259058-A1 | Process for the Preparation of Prostaglandin Analogues and Intermediates Thereof | SCINOPHARM TAIWAN LTD. | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259058-A1 | Process for the Preparation of Prostaglandin Analogues and Intermediates Thereof | PTGIS, PTGES, PTGER1 | MMP12 1655/4885ALDH1A1 965/4885TSHR 1742/4885 |
| US-20110130577-A1 | Process for the Preparation of Prostaglandin Analogues and Intermediates Thereof | PTGIS, PTGES, PTGER1 | MMP12 1655/4885ALDH1A1 965/4885TSHR 1742/4885 |
| US-20130211128-A1 | Process for the Preparation of Prostaglandin Analogues | PTGIS, PTGES, PTGER1 | MMP12 1084/4885ALDH1A1 917/4885TSHR 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.