Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336745 | 0.86 | ABCC1 (0.55) | POLBPTGS2MAPTKDM4EMEN1 | |
| SCHEMBL8185547 | 0.80 | PTGS2 (0.51) | POLBPTGS2MAPTMEN1KMT2A | |
| SCHEMBL8184514 | 0.79 | PTGS2 (0.58) | POLBPTGS2MAPTMEN1KMT2A | |
| SCHEMBL8177997 | 0.79 | PTGS2 (0.61) | PTGS2MAPTKDM4EMEN1NPC1 | |
| SCHEMBL7613253 | 0.78 | PRKCI (0.62) | PRKCI | |
| SCHEMBL8172960 | 0.78 | LMNA (0.49) | POLBPTGS2MAPTLMNAPRKCI | |
| SCHEMBL8179296 | 0.78 | KDM4E (0.49) | POLBMAPTKDM4EMEN1NPC1 | |
| SCHEMBL8170324 | 0.78 | ALDH1A1 (0.49) | POLBMAPTKDM4EMEN1NPC1 | |
| SCHEMBL8180855 | 0.78 | PTGS2 (0.59) | PTGS2MAPTKDM4EMEN1NPC1 | |
| SCHEMBL8178388 | 0.76 | LMNA (0.58) | POLBPTGS2MAPTLMNAPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |