Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019826 | 0.78 | ALDH1A1 (0.37) | TSHRMEN1KMT2ARXFP1KDM4E | |
| SCHEMBL9845265 | 0.77 | TSHR (0.40) | TSHRMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL9019796 | 0.74 | CYP3A4 (0.41) | TSHRMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9845279 | 0.73 | MEN1 (0.39) | TSHRMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8190974 | 0.73 | MEN1 (0.54) | TSHRMEN1KMT2AHPGD | |
| SCHEMBL9019807 | 0.71 | PDE3A (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9845272 | 0.71 | CYP3A4 (0.35) | TSHRMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9845278 | 0.70 | SYK (0.31) | TSHRMEN1KMT2A | |
| SCHEMBL7968026 | 0.70 | ADORA2B (0.41) | CNR2ADORA2BRXFP1KDM4EALDH1A1 | |
| SCHEMBL8177043 | 0.69 | ADORA2B (0.46) | CNR2ADORA2BRXFP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006573-A1 | ANTIVIRAL ALKYL SUBSTITUTED PURINE DERIVATIVES AND THEIR PREPARATION | Kemijski inštitut (SI) | 2000-02-10 | — | — | WO | disclosed |