Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819817 | 0.78 | TSHR (0.36) | TDP1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL818078 | 0.76 | KDM4E (0.35) | TDP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL23364360 | 0.76 | SETD7 (0.36) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL818870 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL818893 | 0.75 | TDP1 (0.31) | TDP1ALDH1A1 | |
| SCHEMBL818604 | 0.73 | TSHR (0.40) | ALDH1A1GAAHSD17B10 | |
| SCHEMBL28275195 | 0.63 | LMNA (0.30) | — | |
| SCHEMBL818207 | 0.62 | KCNH2 (0.38) | TDP1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30828319 | 0.61 | HSD17B10 (0.34) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL28067834 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |