SCHEMBL818893

SCHEMBL818893

COC(=O)C1=CC(C)=CC=CC1C(=O)OC

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 2/20 0.30
USP2 O75604 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818870 0.78 KDM4E (0.32) ALDH1A1
SCHEMBL817772 0.77 ALDH1A1 (0.34) TDP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL818072 0.75 TDP1 (0.32) TDP1ALDH1A1
SCHEMBL23364360 0.75 SETD7 (0.36) MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL818971 0.74 ALDH1A1 (0.39) MAPTALDH1A1SMN1; SMN2
SCHEMBL12228858 0.65 ALDH1A1 (0.38) TDP1MEN1MAPTKMT2AL3MBTL1
SCHEMBL819759 0.64 KCNH2 (0.34) L3MBTL1ALDH1A1
SCHEMBL8767264 0.63 HSD17B10 (0.33) TDP1MEN1MAPTKMT2ANPSR1
SCHEMBL18063306 0.61 HSD17B10 (0.33) MAPTKMT2AL3MBTL1ALDH1A1
SCHEMBL7929530 0.61 DNTT (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236908-B2 Components and catalysts for the polymerization of olefins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
US-20110269927-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed