SCHEMBL818870

SCHEMBL818870

COC(=O)C1=CC=CC=CC1C(=O)OC

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GLA P06280 2/20 0.32
GAA P10253 2/20 0.32
HPGD P15428 2/20 0.32
CASP1 P29466 2/20 0.32
CASP7 P55210 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ATM Q13315 1/20 0.32
POLB P06746 1/20 0.31
KCNH2 Q12809 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818893 0.78 TDP1 (0.31) ALDH1A1
SCHEMBL817874 0.75 TSHR (0.37) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL23364360 0.71 SETD7 (0.36) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL817439 0.71 ALDH1A1 (0.41) KDM4EALDH1A1TSHR
SCHEMBL28234221 0.70 DNTT (0.33) ALDH1A1
SCHEMBL818165 0.70 TSHR (0.45) KDM4EALDH1A1HSD17B10POLBTSHR
SCHEMBL7929530 0.68 DNTT (0.37) ALDH1A1HSD17B10POLBTSHR
SCHEMBL12228858 0.68 ALDH1A1 (0.38) KDM4EALDH1A1GLAGAAHPGD
SCHEMBL819759 0.67 KCNH2 (0.34) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL8767264 0.67 HSD17B10 (0.33) KDM4EALDH1A1GLAGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236908-B2 Components and catalysts for the polymerization of olefins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
US-20110269927-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed