Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038271 | 0.70 | CA2 (0.45) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28337645 | 0.65 | UGT2B7 (0.52) | MAPTUGT2B7MEN1KMT2AATM | |
| SCHEMBL28337642 | 0.65 | UGT2B7 (0.52) | MAPTUGT2B7MEN1KMT2AATM | |
| SCHEMBL434216 | 0.62 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL30033673 | 0.62 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL600527 | 0.62 | UGT2B7 (0.68) | UGT2B7MEN1KMT2AATMSLC6A2 | |
| SCHEMBL28413868 | 0.62 | MAPT (1.00) | MAPTUGT2B7MEN1KMT2ASLC6A2 | |
| SCHEMBL11356021 | 0.62 | SLC6A4 (0.58) | MAPTUGT2B7GABRA1GABRG2GABRB3 | |
| SCHEMBL15631192 | 0.62 | LMNA (0.41) | MEN1KMT2A | |
| SCHEMBL29498267 | 0.61 | PGK1 (0.62) | MAPTUGT2B7MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |