Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177719 | 1.00 | SLC6A4 (0.39) | SLC6A4SLC6A3KDM4EMAPTPPARG | |
| SCHEMBL6180652 | 0.83 | PPARG (0.52) | SLC6A4SLC6A3KDM4EMAPTPPARG | |
| SCHEMBL8170155 | 0.73 | MEN1 (0.44) | SLC6A4SLC6A3DRD2MEN1KMT2A | |
| SCHEMBL8798591 | 0.69 | HTR1A (0.56) | SLC6A4KDM4EMAPTPPARGPPARA | |
| Hydrochloric Acid SCHEMBL8957939 | 0.69 | HTR1A (0.55) | SLC6A4KDM4EMAPTPPARGPPARA | |
| Hydrochloric Acid SCHEMBL8958128 | 0.69 | HTR1A (0.55) | SLC6A4KDM4EMAPTPPARGPPARA | |
| SCHEMBL7793671 | 0.67 | ADRA1D (0.62) | SLC6A4MAPTHTR1ADRD2SLC6A2 | |
| SCHEMBL8177718 | 0.67 | DRD2 (0.38) | KDM4EMAPTPPARGPPARAHTR1A | |
| Hydrochloric Acid SCHEMBL7029018 | 0.66 | ADRA1D (0.61) | SLC6A4MAPTHTR1ADRD2SLC6A2 | |
| Hydrochloric Acid SCHEMBL7029024 | 0.66 | ADRA1D (0.61) | SLC6A4MAPTHTR1ADRD2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110943-A | AN ANTIPSYCHOTIC AGENT, ANTIDEPRESSANT AND ANXIOLYTIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |