SCHEMBL8184648

SCHEMBL8184648

C=CC(=O)NC(CCCNC(=N)N)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 11/20 0.45
▸ C3AR1 Q16581 1/20 0.38
▸ DDAH1 O94760 1/20 0.37
▸ GNPAT O15228 1/20 0.37
▸ FOLH1 Q04609 2/20 0.37
▸ ZDHHC20 Q5W0Z9 1/20 0.35
▸ ZDHHC2 Q9UIJ5 1/20 0.35
▸ NOD1 Q9Y239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628303 1.00 TGM2 (0.45) TGM2C3AR1DDAH1GNPATFOLH1
SCHEMBL8177277 0.88 C3AR1 (0.48) TGM2C3AR1DDAH1GNPATFOLH1
SCHEMBL8177335 0.86 TGM2 (0.55) TGM2FOLH1ZDHHC20ZDHHC2
SCHEMBL28776336 0.86 FOLH1 (0.38) TGM2C3AR1FOLH1NOD1
SCHEMBL935421 0.86 TGM2 (0.38) TGM2C3AR1DDAH1ZDHHC20ZDHHC2
SCHEMBL28776339 0.86 FOLH1 (0.38) TGM2C3AR1FOLH1NOD1
SCHEMBL28883698 0.85 NPY4R (0.42) TGM2FOLH1ZDHHC20ZDHHC2
SCHEMBL28883697 0.85 NPY4R (0.42) TGM2FOLH1ZDHHC20ZDHHC2
SCHEMBL12971304 0.84 C3AR1 (0.43) C3AR1GNPATFOLH1NOD1
SCHEMBL29005731 0.84 C3AR1 (0.43) C3AR1GNPATFOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110684150-B Amino acid nano hydrogel and preparation method and application thereof 南方医科大学 2021-05-11 — — CN claimed
CN-110684150-A Amino acid nano hydrogel and preparation method and application thereof 南方医科大学 2020-01-14 — — CN claimed
US-20210388142-A1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON & JOHNSON VISION CARE, INC. 2021-12-16 — — US disclosed
CN-110684150-B Amino acid nano hydrogel and preparation method and application thereof 南方医科大学 2021-05-11 — — CN disclosed
CN-110684150-A Amino acid nano hydrogel and preparation method and application thereof 南方医科大学 2020-01-14 — — CN disclosed
US-10017461-B2 Method of making ligand functionalized substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-07-10 — — US disclosed
US-9650470-B2 Method of making ligand functionalized substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-05-16 — — US disclosed
US-20140364519-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2014-12-11 — — US disclosed
US-8846203-B2 Method of making ligand functionalized substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 — — US disclosed
EP-2522692-B1 Ligand monomers and copolymers made therewith 3M INNOVATIVE PROPERTIES CO (US) 2014-06-18 — — EP disclosed
US-20140087445-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-03-27 — — US disclosed
US-8652582-B2 Method of making ligand functionalized substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-18 — — US disclosed
EP-2522692-A1 Ligand monomers and copolymers made therewith 3M Innovative Properties Company (US) 2012-11-14 — — EP disclosed
US-20110184078-A1 Ligand Functionalized Substrates SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2011-07-28 — — US disclosed
US-20110033633-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2011-02-10 — — US disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 — — US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 — — EP disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10017461-B2 Method of making ligand functionalized substrates SPR, SELPLG, SIGLEC7 TGM2 2172/4885C3AR1 1331/4885DDAH1 1482/4885
US-20140364519-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES SPR, SELPLG, SIGLEC7 TGM2 2172/4885C3AR1 1331/4885DDAH1 1482/4885
US-20110033633-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES SPR, SELPLG, SIGLEC7 TGM2 2172/4885C3AR1 1331/4885DDAH1 1482/4885
US-20140087445-A1 METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES SPR, SELPLG, SIGLEC7 TGM2 2172/4885C3AR1 1331/4885DDAH1 1482/4885
US-20210388142-A1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM ARGLU1, BCAT2, BCAT1 TGM2 137/4885C3AR1 950/4885DDAH1 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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